Maybe it was all those years of futility for the Phillies. Or the shadows cast by New York City to the north and Washington, D.C., to the south. Whatever the reasons, Philadelphia has earned the melancholy distinction of being America's most depressed city, followed closely by Detroit and St. Petersburg, Florida. Men's Health compiled this list based on antidepressant sales, courtesy of NDC Health; suicide rates, from the Centers for Disease Control and Prevention (CDC); and the number of days inhabitants reported being depressed, based on the CDC's Behavioral Risk Factor Surveillance System, accessed through bestplaces.net.

Where can you find happiness? Texas, that's where. Three of its cities placed in the top four: number one, Laredo; number two, El Paso; and number four, Corpus Christi.

The 20 Happiest Cities

1. Laredo, TX: A+
2. El Paso, TX: A+
3. Jersey City, NJ: A+
4. Corpus Christi, TX: A+
5. Baton Rouge, LA: A
6. Honolulu, HI: A-
7. Fresno, CA: A-
8. San Jose, CA: A-
9. Lincoln, NE: B+
10. Bakersfield, CA: B+
11. Buffalo, NY: B+
12. Anchorage, AK: B+
13. Stockton, CA: B+
14. Shreveport, LA: B+
15. (3-way tie) Madison, WI: B
16. (3-way tie) Montgomery, AL: B
17. (3-way tie) Des Moines, IA: B
18. Wichita, KS: B
19. (tie) Sacramento, CA: B
20. (tie) Omaha, NE: B

The 20 Most Depressed Cities

1. Philadelphia, PA: F
2. Detroit, MI: F
3. St. Petersburg, FL: F
4. St. Louis, MO: F
5. Tampa, FL: F
6. Indianapolis, IN: F
7. (3-way tie) Mesa, AZ: F
8. (3-way tie) Phoenix, AZ: F
9. (3-way tie) and Scottsdale, AZ: F
10. Cleveland, OH: F
11. New York, NY: D-
12. Salt Lake City, UT: D-
13. Atlanta, GA: D
14. (3-way tie) Yonkers, NY: D
15. (3-way tie) Pittsburgh, PA: D
16. (3-way tie) Kansas City, MO: D
17. (3-way tie) Long Beach, CA: D
18. (3-way tie) Los Angeles, CA: D
19. (3-way tie) Nashville, TN: D
20. Portland, OR: D

Back to Top